For the swine industry, the most terrible thing is the disease. Once onset, treatment becomes a major problem for the farm. At the time of onset, sick pigs often experience high temperatures and are accompanied by symptoms such as constipation and loss of appetite. Constipation and loss of appetite are a major obstacle to curing pigs. During the treatment, the addition of microbial feed additives and therapeutic drugs in the feed can improve the body's immune system, speed up the body's self-repair, eliminate or reduce the occurrence of constipation and antifeedant, and help to strengthen the therapeutic effect of the drug.
What is microbial feed additive
Microbial feed additives refer to preparations that use normal microorganisms, their metabolites, or growth-promoting substances in animals to undergo special processing techniques. They can supplement, adjust, or maintain the microecological balance of the animals' intestines to achieve prevention, treatment, and promotion of health. Improve the purpose of production performance. Microbial feed additives include not only normal microbial members, especially dominant seedlings, but also some preparations that promote the growth and reproduction of normal microbiota, which can produce certain biological or ecological effects.
Mechanism of Action of Microbial Feed Additives
The mechanism of action of microbial feed additives is the result of a comprehensive effect and is now described as follows:
Maintaining the Intestinal Microecological Balance of Animals
A variety of microbial communities grow in the intestines of healthy livestock and poultry. Various microbial communities are interdependent and restrict each other and constitute a microecological balance of the intestine. A well-balanced gut microflora plays an important role in fighting infections from pathogenic microorganisms. However, under certain conditions, animals, such as stress, disease, and long-term use of broad-spectrum antibiotics, may cause damage to the microecological balance in the gut. The feeding of microbiological feed additives, beneficial microorganisms to reproduce quickly after reaching the digestive tract of animals, the absolute number of absolute advantages, coupled with their growth and metabolism caused by anaerobic environment, which greatly inhibited the growth and reproduction of those aerobic pathogenic microorganisms. At the same time, antibacterial substances, organic acids, etc. can also be produced to reduce the intestinal pH, compete with harmful bacteria for nutrients and attachment sites, and inhibit the growth of other pathogenic microorganisms, thereby maintaining or restoring the balance of microbial flora in the gut.
Nutritional supplements
Many kinds of amino acids, B-vitamins, and other useful metabolites produced by beneficial bacteria in the microbial feed additive metabolism in the intestine can be used as nutrients for livestock and poultry.
Prevent the generation of harmful substances
Microbial feed additives can promote the digestion and absorption of nutrients, which can reduce the production of ammonia and other spoilage substances. Studies have shown that normal microbial populations constitute the body's chemical and biological barriers. Microbial metabolites such as acetic acid, propionic acid, lactic acid, anti-miyao peptides, and other active substances form a chemical barrier; microbial flora is colonized in an orderly manner on the surface of the mucous membrane, skin, or between cells to form a biological barrier, and these barriers can prevent Colonization of pathogenic microorganisms acts as a placeholder and competes for nutrients.
Barriers and biological barriers. Microbial metabolites such as acetic acid, propionic acid, lactic acid, anti-miyao peptides, and other active substances form a chemical barrier; microbial flora is colonized in an orderly manner on the surface of the mucous membrane, skin, or between cells to form a biological barrier, and these barriers can prevent Colonization of pathogenic microorganisms acts as a placeholder and competes for nutrients.
Improve immune function
The beneficial bacteria in the microbial feed additive are all good immune activators. They can stimulate the immune organs of the intestines and stimulate the body to produce humoral and cellular immunity. It can increase the antibody level of livestock and poultry or increase the activity of macrophages, enhance the immune function, kill pathogens that invade the body in time, and prevent the occurrence of diseases.
The function of microbial feed additives
Microbiological feed additives can create an anaerobic environment in the intestine through biological detoxification, promote the rapid growth of beneficial anaerobic bacteria in the intestine, generate large amounts of acid, colonize the intestinal tract normally, compete with pathogenic bacteria, and inhibit the growth of pathogenic bacteria Breed; Synthesize vitamins, promote food digestion, help nutrient absorption, and promote metabolism. Overcome the corruption process. It has many functions such as promoting the growth and development of animals, digesting and absorbing nutrients, biological antagonism, increasing feed conversion rate, adjusting the balance of normal flora, and improving immunity, and in particular preventing the inactivation of bacterial flora and the invasion of foreign pathogenic bacteria.
Application of Microbial Feed Additives in Actual Production
August 2009, a large-scale pig farm in Kaiyuan City, Liaoning Province, in order to ensure the construction progress, while the second phase of the construction side of the construction. Due to the spread of diseases caused by mosquito bites in the summer season, the outbreaks of outbreaks in the townships surrounding the farms were widespread outbreaks. The construction staff of the farms came from the surrounding epidemic areas and frequent exchanges and ineffective prevention measures on the farms led to the onset of the entire population.
The clinical manifestations of sick pigs
Suddenly, the temperature of the sick pig rose to 41°C, and some reached 42°C. Breathing accelerated, asthma, coughing, sneezing, and thick nose; flushing, redness of the eyes, tears and secretions; , slumber unwilling to exercise, dark yellow urine.
diagnosis
According to the symptoms and necropsy analysis combined with previous treatment cases and other diagnosed as influenza caused by blue ear disease, swine fever, streptococcal mixed infection.
Treatment measures
According to past experience, it is important to control various bacteria. According to the requirements of the growth of pigs in all stages of the preparation of feed for nutrition, in the feed by 0.5% ratio of microbial health additives play a role in "Cheung Baike", with the use of drug treatment. Astragalus polysaccharides were added to the drinking water during treatment, and the fast-acting multidimensional was added. During the severe period, sodium bicarbonate and glucose were added to the water. The pigs were intramuscularly injected and each pig was intramuscularly injected with the broad-spectrum antibiotics lincomycin and isatis root and ceftiofur sodium daily. The two drugs were used alternately. After 7 days of meticulous treatment, the sick pigs did not die and all recovered. The cost of treatment is much lower than the use of drugs such as immune RNA. During the course of treatment, although the sick pigs were high in fever, no constipation and antifeedant were found.
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