Release date: 2017-04-06
Zhang Jin, the New Hope Reproductive Medicine Center of the United States.
The technical details of the world's first nuclear-transplant "three-parent" baby were officially announced on April 3. Zhang Jin, from the New Hope Reproductive Medicine Center of the United States, who is developing technology, said that the baby is in good health and brings new hope to the birth of healthy offspring for families plagued by mitochondrial genetic diseases.
Everyone inherits three genetic material from their parents, the nuclear DNA of the father's sperm (deoxyribonucleic acid), the nuclear DNA of the mother's egg, and the mitochondrial DNA independent of the nucleus in the mother's egg. Defects in mitochondrial DNA leads to mitochondrial genetic diseases.
The papers published by researchers in the journal Reproductive Biomedical Online detail the technical details. According to the paper, the "three-parent" baby was born in New York, USA on April 6, 2016. One-quarter of the Jordanian mother's mitochondria carry the subacute necrotizing encephalopathy gene, which has been aborted four times and gave birth to two children. Also early. To help the woman, the Zhang Jin team used the “three parents†technique to remove the healthy nuclei from the problem egg and put it into the donated egg. The nucleus of the donated egg has been removed beforehand, but the cytoplasm of the mitochondria remains, so that the baby has the mitochondrial genetic material donated to the woman in addition to the parent's gene.
The mitochondrial variation ratio of each tissue cell varies from 2.36% to 9.23%. It is generally believed that the mitochondrial disease needs to be mutated to more than 20%.
At present, the United Kingdom has released the "three parents" baby technology, but due to ethical disputes, the United States and other countries still ban this technology. Zhang Jin introduced that they completed steps such as ovarian stimulation, egg collection, mitochondrial replacement surgery and in vitro fertilization in New York, and the embryos were implanted in Mexican patients who did not limit the "three parents" technique.
In order to re-assemble the nucleus and cytoplasm, the Zhangjin team developed electrofusion technology, which is safer and more acceptable to patients than the previously used virus fusion technology.
“Now we are the first to be able to modify an egg with abnormal mitochondria to contain normal normal mitochondria from healthy egg donors,†said Bart Fozer, editor-in-chief of Reproductive Biomedical Online, in a statement. "This is a major change in technology."
Source: Technology Daily
The bearing structure, fixed film systems and installation of this greenhouse is relatively simple. And due to it, raw material and manufacturing costs are affordable. Except the high strength woven film is higher, other kinds of antidrop film are economical. In general, the comprehensive cost of film greenhouse is lower 30% ~ 50% than the same size and specifications of the other types of greenhouse.
Single Span Greenhouse,Greenhouse Film,Tunnel Greenhouse,Plastic Film Greenhouse
JIANGSU SKYPLAN GREENHOUSE TECHNOLOGY CO.,LTD , https://www.thgreenhouse.com