Release date: 2018-05-25
Researchers in China and the United States have developed a miniature elastic sphere that is similar in size to cells and can measure compressive stress between cells. This technology is expected to be used for early diagnosis of cancer.
Research published in the British journal Nature News on the 14th showed that researchers at Huazhong University of Science and Technology and University of Illinois at Urbana-Champaign used microfluidic chips and elastomeric alginate polymers to make miniatures. Elastic spheres have diameters, mechanics and chemical properties similar to those of cells.
Professor Wang Ning of Huazhong University of Science and Technology added fluorescent nanoparticles to the elastic sphere to quantitatively analyze the deformation of the elastic sphere. Experiments have shown that these bio-compatible microelastic spheres adhere to living cells and can measure the "biological force" at three-dimensional scale.
Wang Ning told Xinhua News Agency that "biological power" is the force produced by living cell "type II myosin", which belongs to an electromagnetic force and plays an important role in cell growth, development and differentiation.
Wang Ning said that using the "bio-power" measurement technology can regulate the physiological micro-environment and achieve the purpose of early diagnosis, treatment and cure of certain complex diseases.
The team used elastic ball technology to find that the "bio-power" produced by malignant tumor-regenerating cells and normal stem cells is different. Wang Ning said that measuring the "bio-power" between cells is expected to be a tool for early diagnosis of cancer and to help explain how synthetic drugs that prevent cancer metastasis work.
Source: Xinhuanet
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