Western medicine pharmacology
1. Hemostatic effect: Mao raspberries resulting water extraction and alcohol precipitation extracts (hereinafter referred to as the water extract) 10g / kg, 20g / kg, 40g / kg were fed to mice, continuous 3d, bleeding time can be shortened by 25% -37 %, clotting time is also significantly shortened, and has the effect of accelerating hemostasis.
2. Antithrombotic: thrombosis tests show that water extract 2g / kg orally, continuous 3d, it can inhibit thrombus formation, and significantly shorten the euglobulin lysis time, Mao raspberries tips can be improved in vivo fibrinolytic enzyme active.
3. Myocardial ischemia: Water Mau berry extract 6g (crude drug) / kg gavage to rats, continuous 3d, 1h after the last administration the animals were sacrificed 1, removal of the heart, for the Langendorff heart perfusion results showed Mao raspberries Can significantly increase coronary flow. The administration according to the above method can also significantly counteract the ischemic electrocardiographic changes induced by pituitrin in rats. In addition, the mouse normobaric and hypobaric hypoxia endurance tests showed that the gavage of the water extract of the raspberry significantly increased the ability of animals to withstand hypoxia.
4. Toxicity: Mushroom water extract was administered to mice at a dose of 80 g/kg. Except for slight anorexia and occasional loose stools, there were no other obvious poisoning symptoms. Therefore, the maximum tolerated dose (mouse orally) is greater than 80 g/kg, which is equivalent to 133 times the amount of humans.
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