Release date: 2016-06-22
A girl born in Congo (cloth) was diagnosed with sickle cell anemia at the age of 5, and a 13-year-old resected part of the ovary was frozen to cope with the huge damage to the ovaries caused by chemotherapy. Relying on these slices, the woman was given a wish at the age of 27 and gave birth to a healthy baby boy.
According to doctors, this is the world's first case, such as this young "freezing ovary" and successful delivery.
Unfortunately, fortunately
The identity of the woman was not made public, and her attending doctor told the details of the treatment in the British magazine "The Reproduction of Humans" on the 10th.
The patient immigrated to Belgium with his family when he was 11 years old. Due to the serious condition, Belgian doctors believe that women need to receive bone marrow transplants, and it is best to receive chemotherapy before this. Considering the serious side effects of chemotherapy on the ovaries and the possibility that a woman might want a child in the future, the doctor developed a plan to remove the right ovarian tissue for cryosection.
When the woman was 13 years old and 11 months old, the right ovary was partially removed. At this time, she had not started menstruation. However, the doctor said she had entered puberty and her chest began to develop.
The bone marrow transplant was successful, but the woman developed a graft-versus-host response and took 18 months of immunosuppressive drugs. At the age of 15 years, the left ovary was diagnosed with a loss of normal function.
Ten years later, the woman wanted the child, and the Isabel de Mestel team at the Erasmus Hospital of the Free University of Brussels took over again. They planted 4 frozen tissue sections into the left ovary of the woman. After 5 months, the woman started menstruation.
However, everything is not easy. The patient's boyfriend was diagnosed with infertility, and the two men had no artificial insemination and had broken hands. Later, the woman had a new boyfriend and was naturally pregnant. She gave birth to a baby boy in November last year and weighed 3.1 kg.
Hope & risk
De Mestel said that the woman's left ovary is all normal.
“This is a happy birth,†De Mestel said. “I am happy for the patient. She has been worried that the operation will not be successful, and she has no other way to have children.â€
According to her, this is the world's first case of this young, frozen ovarian tissue section and successful delivery. Prior to this, adult women gave birth through similar surgery, but no one had done this before the menstrual period.
"We don't know what happens when the ovarian tissue that has not yet fully developed is implanted back into the patient," De Mestel said. "But when I found out that she started ovulating and the hormone levels returned to normal, I was basically sure she was pregnant. ."
This operation has been recognized by many experts. They believe that this brings good news to many young patients with similar needs. However, it is not certain that surgery will be effective for children who have not yet entered adolescence.
Gil Ginsberg, a pediatric oncologist at the Cancer Treatment Center at Children's Hospital of Philadelphia, USA, said: "It is unusual for children to undergo such surgery and become pregnant after many years... this brings hope to those high-risk girls (infertility), but There is still a huge risk."
Source: Zhongxin Net
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