International authorities let you know more about HPV
 | How many HPV pathogenic genotypes are there? |
| According to the US Centers for Disease Control and Prevention (CDC) in 2016, more than 150 types have been discovered, and more than 40 types of HPV can infect male and female genital areas, and HPV of these subtypes can also infect oral cavity through oral sex. Mucosal parts such as the throat that cause cancer or genital warts. Http:// | |
 | How many years increased the number of carcinogenic HPV subtypes recognized by the International Agency for Research on Cancer? |
In 1995, the IARC announced that certain subtypes of human papillomavirus infection are the leading cause of cervical cancer. Confirmed 4 high-risk carcinogenic types in 1995 Increased to 13 high-risk carcinogenic types in 2007 25 high-risk carcinogenic types reached in 2012 How many high-risk carcinogenic types will there be in 2020? |  |
 | Sex, cancer and viral HPV caused by the development of male laryngeal cancer |
 | American scientists have discovered that HPV is causing a new type of head and neck cancer. Male larynx cancer HPV positive 16% in 1985 Male larynx cancer HPV positive 72% in 2005 The HPV of male laryngeal cancer is estimated to be 90% in 2025. Researchers believe that this upward trend is related to the prevalence of oral sex. The incidence of laryngeal cancer caused by HPV infection is expected to be as high as 90% by 2025 and close to 99% of cervical cancer. Gillison, et al. Nature, 2013, 503:330-332 |
 | What is the current type of sexually transmitted HPV in China? |
| The virologist of the Chinese Academy of Medical Sciences reported in 2013 that 30 HPV types were detected in 200 male homosexual swab samples, with a positive rate of 64.5% (129/200), of which 2 were up to 12 co-infections, all 30 The type was detected in all of these groups. It can be seen that the current sexually transmitted HPV subtypes in China have far exceeded 30 types, and the male HPV infection rate is higher than that of females. Peng, et al. J. Clin. Microbiol. 2013, 51(2): 402-408 | |
MasScan ® HPV provides the most comprehensive pathogenic HPV typing test
MasScan ® HPV45 covers IARC2012 and internationally recognized (CE, FDA and CFDA) certified kits
How MasScan ® HPV achieves ultra-high sensitivity and accurate detection
Mass spectrometry laser scanning of samples amplified by PCR and endpoint method dual specific targets. The molecular weight was used for labeling and the results were fully automated. A highly multiplicative response and a precise, sensitive, fast and cost-effective typing method.
High sensitivity of PCR→High throughput of the chip→High precision of mass spectrometry→Automatic analysis results Manual operation < 30 minutes; Final analysis results in 8 hours.
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MS scans MasScan ® 45 kinds of HPV typing spectrum
MasScan ® HPV for the crowd
How to infect HPV to understand the route of infection, only to know effective prevention and timely inspection.
HPV is the most common sexually transmitted infection (STI) virus. Since most virus carriers are not aware that they are infected, they do not know that they may transmit HPV to their sexual partners. Normal people who have sex with a virus carrier without any symptoms can be infected through contact with the vagina, anus or mouth.
HPV infection than women tested positive Notes source, blocking the only source of infection to completely clear the virus.
Identification of multiple HPV genotypes in the human sperm bank Danish scientists conducted the first HPV screening of the world's largest Cryos international sperm bank, and found that the HPV positive rate was as high as 16%, and two-thirds were high-risk, revealing the sperm-propagating HPV pathway. Kaspersen, et al. PLOS ONE, 2011; 6 (3): e18095
The significance of HPV typing detection
Confirm the risk of infection High-risk HPV16 infection develops into CIN3+ to invasive cancer within a few years, but not on carcinogenic HPV61, and it will not develop into cancer for a long time.
Confirmation of continued infection with IARC The publication of certain subtypes of HPV persistent infection is the leading cause of cervical cancer. Most HPV infections are cleared within 1-2 years, and are considered persistent infections when the same or group of HPV genotypes are detected more than twice in more than one year. If the first HPV test results are positive, it is difficult to estimate when to get infected. From infecting HPV to developing cervical cancer, it takes at least 8-10 years of latency, and continuous testing can effectively avoid missed treatment corrections.
Identify who is infected with you When you have sex with an infected person, the HPV you are infected with is the same as the genotype of the infection. Using condom blocking and co-treatment and testing can help correct persistent infections.
Vaccination Guidance Even if you have had a sexual re-vaccination, it may not be completely ineffective. As long as there is no type of vaccine coverage, vaccination is beneficial.
MasScan ® HPV Human Papilloma Virus Tyage Detection
Detection principle: 45 kinds of HPV DNA subtypes were detected by PCR-MS mass spectrometry in two tubes. For the high-risk types 16, 18, 26, 31, 45, 51, 53, 58 and 73 positive samples, HPV oncoprotein gene E6 mRNA activity can be detected.
I tube: high-risk and low-risk high hair style for HPV16 using E and L double gene detection, other carcinogenic types: 18, 26, 31, 33, 35, 39, 45, 51, 52, 53, 56, 58, 59, 66, 67, 68, 70, 73, 82 (including IS39/82 subtype), and high-incidence type 6 and 11 type, a total of 22 types.
II tube: medium and low risk type 2, 5, 8, 30, 34, 40, 42, 43, 44, 54, 55, 61, 62, 64, 69, 70, 71, 72, 81/CP8304, 83, 84 Types 85, 89 and 97, a total of 23 types.
Specimen type: cervical exfoliated cells, secretions, biopsy tissue, in vitro fertilization semen, buccal swabs, anal swabs, urethral swabs or glans and foreskin swabs, swabs on the surface of the carcass.
Sensitivity and specificity: The minimum detection amount is 10 copies/reaction, and the type detected is accurately identified without cross-reaction.
Detection system: PCR instrument + DNA mass spectrometer
Scope of application: Currently used in scientific research and epidemiological investigations.
MasScan ® HPV's unique advantages
MasScan ® HPV technology highlights
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