In July 2016, GlaxoSmithKline's cervical cancer bivalent vaccine Cervarix obtained the marketing approval of the State Food and Drug Administration, becoming the first approved HPV vaccine for cervical cancer prevention in China. Cancer vaccines have once again become the focus of widespread attention in the industry. At present, many research and development companies in this field are Xiamen Wantai Bohai Biological Company under Wantai Biological and Shanghai Zerun Biotechnology Co., Ltd. under Watson Biological in Zhangjiang, Shanghai. However, there is still a company in the field of HPV vaccine research and development. In the sprint, it is Bo Wei Bio in Shanghai International Medical Park.
According to relevant statistics, cervical cancer is the second-highest cancer among women aged 15 to 44 in China. Each year, there are about 130,000 new cases, and cervical cancer accounts for more than 28% of the world's total. On a global scale, On average, a new case was detected every minute, and one woman died of cervical cancer every two minutes.
Before the approval of GSK Shirley, the domestic vaccination of HPV vaccine was achieved through group delegation to Hong Kong. However, the risks and safety hazards also made many women hesitate, and the land and forest insurance did not work. How to find safety? Vaccination at the clinic is also an annoying thing.
GSK Shirley was approved, so that everyone can see the dawn of HPV vaccine in the Mainland. It is reported that this vaccine is expected to enter the market in May this year.
Bo Wei Bio stands out
There are many companies engaged in the research and development of HPV vaccines nationwide, but there are not many clinical trials. There are also two Shanghai companies, namely Zerun Bio and Bowei Bio. The former is located in Zhangjiang Hi-Tech Park, the latter is located in Shanghai International Medical Park, and Zhang Gaoxia is the founder.
Zhang Gaoxia is a native of Yichang, Hubei Province. He came to Shanghai in 2000 and has worked in Shanghai Fosun Pharmaceutical Genetic Engineering Drug Research Center and Shanghai Huisheng Bioengineering Co., Ltd. (Shanghai Zerun Bio). He has more than 10 years of experience in genetic engineering drugs and vaccine development.
The 2-valent HPV vaccine was once the project led by Zhang Gaoxia. However, he is more optimistic about the development of 4- and 9-valent HPV vaccines with both technical advantages and market competitiveness. In order to avoid patent disputes at home and abroad, Bo Wei has independently developed a new yeast expression system that can be widely applied to genetically engineered recombinant particles. Research and development of new projects for cancer vaccines and drugs.
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