The truth about genetic coding
CRISPR - What is it that CRISPR can't do?
Today, you can read about CRISPR in almost every science or medical journal. Seven years ago, since the Clip-Cas9 method of changing the rules of the game was first used for genome editing, all walks of life are exploring its infinite possibilities. CRISPR - What is it that CRISPR can't do?
Biochemists around the world are working around the clock to test the boundaries and limitations of this innovative approach. However, methods continue to innovate and evolve, from large pharmaceutical companies to agriculture, food science, medicine, botany, energy, manufacturing, chemistry, and even military, and everyone is annoyed by the unlimited potential of this approach.
Infinite possibilities <br> This complex gene editing technique is more advanced than the DNA modification method used to make insulin. Gene editing with CRISPR is said to be as simple as modifying computer code with the right software. In addition, the CRISPR system is not only simple but also faster and cheaper than previous methods. In addition to the expertise, all that is needed is a suitable laboratory equipment and an example of a carefully selected clustered, regularly spaced short palindromic repeat (or simply CRISPR).
Using these repetitive spiral chains, scientists can accurately locate, cut, and even replace fragments of genetic material, fundamentally altering the DNA of any organism on the planet, including bacteria, viruses, mold, plants, corals, insects, reptiles, birds. , fish, mammals, and of course humans.
A new era of medical advancement <br> There is more than one good news about CRISPR. Countless, scientists now have more confidence than ever to find ways to cure cancer and other malignant diseases. We are about to enter a new era of detection, treatment and even prevention of disease. Early research on sickle cell anemia and cystic fibrosis has progressed. Next is cancer and HIV. Indeed, we will soon be able to eliminate DNA strands that are predisposed to hereditary diseases.
This may be the most exciting potential use of CRISPR, but it will also lead to debates in various countries. There is a subtle line between treatment (healing of the disease) and enhancement (self-promotion, similar to plastic surgery), illness (deafness, dwarfism) and disease. Moreover, there is a difference between gene editing and gene selection, or germline modification. The former can be used in embryos to reduce the risk of genetic diseases, while the latter can be used to reduce the likelihood of being overweight or having brown eyes. Discussing the feasibility of gene coding and gene selection may become a political hot spot in the future. Assume that if common sense prevails, the future of CRISPR will assume primary responsibility and be implemented in practice, and its medical application has far-reaching implications. Soon, we will have the ability to alleviate human suffering in ways never before possible.
The new door will open to disease research, organ transplants and drug discovery. As CRISPR develops a new set of chemicals, compounds and specially designed molecules, new drug development will become more frequent. Mother Nature may soon become a fair game, and the scientific community may soon consider saving endangered species and bringing endangered coral reefs and other ecosystems back to life. If this doesn't make environmentalists excited, scientists will explore new possibilities for biofuels and environmentally friendly alternative energy development.
Of course, a variety of companies will line up one by one to realize their potential benefits. Manufacturers will use new materials that are lighter, stronger or less expensive to produce. The food industry will also welcome its own happy moments, vegetables are healthier and fruits are more varied. Botanists will have new ways to study plants, and zoologists will have new ways to study animals.
Of course, this will not happen immediately. As we realize the inherent limitations of this new and powerful progress, we will face the challenges and the road ahead will be bumpy. The CRISPR app may have unlimited potential. Humans will win a point. In fact, we may be on the edge of a cliff that makes the world a better place.
Equipped with a lab for CRISPR work
CRISPR is a very sophisticated process that requires expertise, precision and highly controlled laboratory equipment. If you are a scientist who wants to use CRISPR technology, you need to equip the lab with the right equipment to start the experiment.
When preparing samples, the laboratory should include a homogenizer, a centrifuge, and an oscillator. To extract small amounts of RNA from difficult-to-handle samples, you need a high-quality homogenizer. Since the CRISPR work involves multiple sample sizes, the homogenizer should have flexibility in use. Statistics show that linear motion can decompose samples more efficiently than horizontal motion, thereby increasing the extraction rate and ultimately increasing the number of available samples.
Not all centrifuges are the same. OHAUS offers high quality refrigerated centrifuges with a variety of rotors, so researchers can make repeatable results without worrying about machine wear.
The durability of the orbital oscillator is also a problem. OHAUS has a variety of oscillators with different constructions to withstand temperature fluctuations, including large-loaded circumferential shakers, mixers and extreme environmental shakers that can withstand up to 100% humidity. Since hatching usually occurs at night, the last thing scientists want to do is go back to the lab to find a machine failure, or an experiment failure. This is why reliable laboratory equipment is critical to the work of CRISPR.
Regardless of where the future will bring scientists, OHAUS will always provide them with long-lasting precision instruments and strong support.
CRISPR is a very sophisticated process that requires expertise, precision and highly controlled laboratory equipment. If you are a scientist who wants to use CRISPR technology, you need to equip the lab with the right equipment to start the experiment.
When preparing samples, the laboratory should include a homogenizer, a centrifuge, and an oscillator. To extract small amounts of RNA from difficult-to-handle samples, you need a high-quality homogenizer. Since the CRISPR work involves multiple sample sizes, the homogenizer should have flexibility in use. Statistics show that linear motion can decompose samples more efficiently than horizontal motion, thereby increasing the extraction rate and ultimately increasing the number of available samples.
Not all centrifuges are the same. OHAUS offers high quality refrigerated centrifuges with a variety of rotors, so researchers can make repeatable results without worrying about machine wear.
The durability of the orbital oscillator is also a problem. OHAUS has a variety of oscillators with different constructions to withstand temperature fluctuations, including large-loaded circumferential shakers, mixers and extreme environmental shakers that can withstand up to 100% humidity. Since hatching usually occurs at night, the last thing scientists want to do is go back to the lab to find a machine failure, or an experiment failure. This is why reliable laboratory equipment is critical to the work of CRISPR.
Regardless of where the future will bring scientists, OHAUS will always provide them with long-lasting precision instruments and strong support.
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