China Develops First Genetic Engineering Vaccine for Poultry Infectious Diseases

The Yangtze University of Hubei Province took five years to tackle the problem and developed China's first genetic engineering vaccine for poultry infectious diseases. The experts group organized by the Hubei Provincial Department of Science and Technology recently confirmed that the research project has reached an internationally advanced level and has completely independent intellectual property rights, which has significant application value. Five years ago, the Yangtze University carried out the “Development and Research of Genetically Engineered Vaccine for Infectious Bursal Disease” project. Infectious bursal disease is a chicken immunosuppressive infectious disease caused by infectious bursal disease virus infection. It has acute and highly contagious characteristics and can spread rapidly in chickens. Because of the immunosuppression that it produces, it is often accompanied by the failure of some vaccination immunizations, resulting in a high incidence of disease and mortality, which causes great harm to the chicken industry. Because current vaccines are mostly live attenuated vaccines, they often cause immunosuppression, interfere with the immune function of other vaccines, and do not provide protection against the infection of very virulent strains that have emerged in recent years, and have defects such as high production costs. The improvement of vaccines and the development of new vaccines are becoming front-end contents of current research in the veterinary medicine industry at home and abroad. The new oil emulsion vaccine of the genetic engineering subunit of the Infectious Bursal Diseases (IBDV) vaccine developed by the Yangtze University has solved the above problems to some extent. This vaccine is also the first self-developed Chinese medicine with independent intellectual property rights. The genetic engineering vaccine for poultry infectious diseases has now applied for patent protection. The results of the immunization protection experiment conducted by the Chinese Veterinary Drug Surveillance Agency showed that the vaccine is non-toxic, does not cause damage to the bursal of chickens, does not interfere with the immune function of other vaccines, and the production cost is lower than other Chinese medicines currently used. Inactivated vaccines have high development and application value.

Amino Acid Series

L-serine, as a basic amino acid of protein, is widely used in medicine, food, cosmetics and other industries. At present, the global market demand for L-serine is 10000t / A. L-serine is a non essential amino acid, which is an important precursor involved in the synthesis of intracellular biological substances such as purine, pyrimidine and phospholipid. L-serine is a raw material for compound amino acid infusion, and can also be used as a raw material for light chemical industry . In addition, L-serine is widely used in advanced cosmetics at home and abroad because of its special wettability and moisture retention

D-serine is one of the most important D-type amino acids in mammals, which is about 1 / 3 of the total free serine. It has been found that high concentration of D-serine exists in the higher center of higher animals, including human beings, and it plays an important role in neurotransmitter. It is found that D-serine plays an important role in the corpus cavernosum and lower esophageal sphincter of mice.

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