Release date: 2016-08-03
Looking back at the most bizarre scientific report in 2014, the study “Entering the blood of young mice into old mice†is definitely worth mentioning. Studies have shown that this animal test can improve the memory and learning ability of older mice and make them younger.
This "vampire"-style anti-aging research has not only emerged in recent years.
"suck" young blood and return to youth?
A few decades ago, a "parabiosis studies" attempted to establish a connection between old and young animals to achieve fluid circulation. In recent years, several studies have shown that young blood can rejuvenate old muscles, heart, brain and other organs. Some scientists are trying to find specific mechanisms and factors for young blood to achieve "rejuvenation."
In 2014, Stanford University neuroscientist Tony Wyss-Coray established a blood circulatory system between old and young mice and found that repeated input of young plasma can make the brains of older mice younger.
As an important turning point, Tony Wyss-Coray founded the company Alkahest and launched an unprecedented clinical trial to enter healthy, young plasma for 18 patients with Alzheimer's disease. They judged the safety and efficacy of the trial by assessing the recovery of typical symptoms such as patient cognition.
Of course, this clinical study in 2014 is free of charge. Wyss-Coray expects that results will be available by the end of 2016.
In addition, a similar study is being conducted in a Korean hospital to determine whether cord blood or plasma can prevent aging.
In 2016, the first clinical trial will be launched
As a startup, Ambrosia recently announced the launch of its first clinical trial to test the effects of young blood anti-aging.
According to clinical trial information registered on the official website of ClinicalTrials.gov, Ambrosia will recruit 600 subjects. It is worth noting that this project requires participants to pay $ 8,000, including plasma, testing, ethics review, medical insurance and other expenses. Of course, only healthy people over the age of 35 can apply for the trial, and they will import young plasma from healthy people under the age of 25.
Jesse Karmazin, the company's co-founder and chief scientist, and a 31-year-old doctor, said the subjects would enter about 1.5 liters of young blood in two days. Before the test and one month after the infusion, the researchers will collect their blood and test more than 100 indicators including hemoglobin levels and inflammatory markers.
Karmazin said that this clinical trial has passed an ethical review. However, his review does not refer to the US FDA, but to the Business Ethics Committee because they believe that plasma input is a well-established and standard treatment program.
The company announced that it has registered 3 subjects and they expect the first trial to be launched in late August.
Questioning
However, some ethicists and scientists have a negative attitude on whether it is charging fees or the experiment itself. Even Tony Wyss-Coray also questioned: "At present, there is still no clinical evidence to prove that this anti-aging project is beneficial. They just use the commercial gimmick to live up to the trust of the people."
According to Leigh Turner, a bioethicist at the University of Minnesota, this “ridiculous†clinical trial reminds us of the need to revisit clinical trials registered by private, for-profit clinics, which are often not legal.
Source: Bio-Exploration
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