Release date: 2018-03-14
Always afraid that even if a bandage is applied, will the wound still leave scars? Does the process of changing gauze always feel pain? Don't worry, this is not about the health care products, but to introduce a new biocompatible bandage. Although it is still in the clinical testing stage, it has shown enough results.
Whether in medical research or applied medicine, the repair of skin tissue and the prevention of scarring are important issues, because scars and normal skin are very different: it has no sweat glands or hair follicles, and it is not elastic in itself, and It is more sensitive to UV radiation than normal skin.
Now from the NUST MISiS Inorganic Chemistry Laboratory, a research team led by Dr. Anton Manakhov has developed a new medical material: a multi-layer "active bandage" that not only It can increase the rate of regeneration of damaged tissues and avoid serious scars caused by burned or damaged skin (such as acne and fungal infections).
The bandage is composed of polycaprolactone (polycaprolactone). This layer of polymer is electroformed. The metal or composite material is deposited on the core film by electroforming. The process of its separation) is biodegradable and biocompatible. After a period of time, the fiber will automatically "dissolve" without any side effects, and this will also eliminate the need to replace or remove the bandage. Additional pain applied to the patient.
However, only such an effect is not enough. The research team has developed a technique for moving a carboxyl group (-COOH) to the surface of a polymer. Once the polymer is attached to a hydrophilic group, the biomolecule can be immobilized. Plasma treated material surface. In this way, the research team can add modifications to the layer base, such as adding nano-silver particles or antibiotics that increase the antibacterial effect and successfully reduce the inflammatory response.
In addition, they also added a layer of human plasma components, why add this part? One of the lab's members, Elizabeth Pamija, explained: "The plasma contains growth factors, fibrin, and other important proteins that promote cell growth, which brings healing to our bandages. ."
Proteins in the plasma provide extraordinary medical results for this material. According to a series of clinical tests conducted by the Research Institute of Experimental and Clinical Medicine (Russia, Novosibirsk, Russia), the results are shown in an in vitro environment. Damaged tissue regenerates twice as fast as normal bandages, and soon the research team will begin in vivo testing. Once this product is clinically tested and goes on the market, it will be an exciting news for people who are suffering from severe burns or who are annoyed by scars on their faces.
Scientists develop biocompatible anti-burn nanofibers that act as 'living bandages'
Biodegradable Bandages Designed to Accelerate Regeneration of Damaged Tissues
“Living bandagesâ€: NUST MISIS Scientists Develop Biocompatible Anti-burn Nanofibers
Grafting of carboxyl groups using CO2/C2H4/Ar pulsed plasma: Theoretical modeling and XPS derivatization
Source: TechNews Technology News
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