Release date: 2014-12-08
Researchers from the University of Uppsala, Sweden, published an article entitled "Smoking Is Associated with Mosaic Loss of Chromosome Y", stating that men with smoking habits are more likely to lose Y chromosomes than men who are not smokers. Times. This finding may explain why for most cancers, men are more likely to have cancer and cancer than women, and why smoking affects men more than women.
The research was published in the December 5th issue of Science.
In traditional theory, scientists interpret the loss of the Y chromosome as that it cannot contain enough important genetic information, so it is optional. In this process, any important gene is transferred from Y to other chromosomes, and sex decides to take a different route. Some scientists even speculate that the human Y chromosome was only about 10 million years before all the genes on the Y chromosome were lost. Some scholars believe that the loss of the Y chromosome is associated with an increased risk of non-hematologic tumors in older men.
In this article, the researchers analyzed more than 6,000 male data and calculated various health and behavioral factors such as their age, exercise habits, cholesterol levels, education status, and alcohol intake.
Researchers have found that this chromosome, which is crucial for sex determination and sperm production, often disappears in the blood cells of smokers, and people who never smoke or have quit smoking have fewer Y chromosomes in their blood cells. The researchers believe that this effect seems to be dependent on different doses, and some of the men who have quit smoking will regain the Y chromosome.
Although the loss of the Y chromosome is a contributing factor to the development of cancer, it is said that only the missing chromosomes lead to further development of cancer, but these findings will be related to this preventable risk factor: smoking, and the most common mutations in the human body. One: Y chromosome loss is linked together, which is of great significance for the future analysis of cancer and the evolution of Y chromosome.
Regarding the loss of the Y chromosome, a group of researchers recently proposed a new hypothesis. They studied the genetic information of more than 4,000 beetles and proposed "why some species have Y chromosomes lost, while others (such as Humans have retained a new theory of it, called the "brittle Y chromosome hypothesis."
The idea of ​​biologists is that the fate of the Y chromosome is deeply influenced by how meiosis or sperm production works in a living organism. They believe that the fusion or recombination of X and Y genetic information can serve as a powerful clue that the species is at risk of Y chromosome loss during sperm production. Previous work suggests that the Y chromosome is missing because it carries fewer important genes.
The X and Y chromosome genes control the sex determination of humans, the XY chromosome combination is male, and the XX chromosome combination is female. Researchers have studied the evolution of these chromosomes, in part to understand more about human evolution and disease. Certain diseases, such as hemophilia, are only associated with genes on the sex chromosome.
Source: Biopass
Applicator Rod Series,Wire Wound Rod,Wet Film Applicator Rods,Applicator Rod
Ningbo Carest Medical Instrument Co.,ltd , https://www.carestmed.com